Guardians Of The Galaxy (2014) - Set Mainly in Space

Kevin Feige spoke with SFX where he said that the GOTG film will be set apart from the other Marvel films:

Guardians and Thor will take the brunt of the cosmic side of the universe, particularly Guardians, which is 95% in space… It’s much more of a standalone film [though] it takes place in the same universe.

The film is scheduled to hit theaters on 01 August 2014.